One of the most interesting and provocative papers published by Tom Alber is this gem:

The role of mobility in the substrate binding and catalytic machinery of enzymes.

This pdf includes the article and a transcript of the fun discussion that followed Greg Petsko’s presentation, featuring Tom Steitz, Hans Frauenfelder, Johann Deisenhofer, Martin Karpus and others.

A few people have asked me for this paper - because it is hard to find in print and doesn’t seem to be freely available online - so I thought I would post my scan of a hardcopy!