Episode 16: Cruel Kinase Summer
We chat about a revolving door of consortium meetings for Jaime, follow up on the OMB proposed rule, two mini-protein kinase preprints, and differences between blogs and scholarly work.
News Links:
Preprints/Blogs:
The Tortured Proteins Department, Episode 16
The Tortured Proteins Department, Episode 15
Episode 15: Daylight
We chat about the conformational ensembles conference, NIH-proposed policy changes, 4! preprints, & running.
NIH News:
- OMB Proposal
- Blog Post Summary on OMB Proposal
- RFI to Cap the Number of Simultaneous Research Project Grants (NOT-OD-26-086)
- NIH Director’s Early Independence Award
Preprints:
The Tortured Proteins Department, Episode 14
Episode 14: Mastermind
We chat about NIH strategic plan comments, AI lab guidelines, preprints on cryo-EM vitrification and automated image processing, and training scientists for the future.
NIH Strategic Plan Comments (Due 5/26):
Preprints:
- Cooling fast and slow: Characterising the effects of vitrification in cryo-EM and the subsequent recovery of equilibrium populations
- cryoAgent: An agentic workflow for robust and adaptive end-to-end cryo-EM image processing
Other Links:
The Tortured Proteins Department, Episode 13
Episode 13: Long Live!
We chat about preprints, AI grad students, the diffUSE project, an April Fools blog, NIH funding news, and the Fraser Lab “broken monitor” April Fools’ Day prank — caught live during recording!
Preprints:
- Intrinsic dataset features drive mutational effect prediction by protein language models
- Ribosome Molecular Aging Shapes Translation Dynamics
AI Grad Student Articles:
Other Links:
NIH News:
The Tortured Proteins Department, Episode 12
Episode 12: Science-ing Through the Lightning Strikes
We chat about the Olympics, NIH bureaucracy (grants & leadership), preprints, 12 episodes of TTPD!, Claude Code & Slack Apps, and the San Francisco Half.
Preprints: