Longtime friend of the lab, Michael Wall, will be visiting and deliver a seminar on his pioneering work using diffuse X-ray scattering and molecular dynamics to study proteins.
November 2nd, 2023 4:00pm in GH S201
Diffuse X-Ray Scattering to Shed Light on Protein Dynamics
Michael Wall, Los Alamos National Laboratory
Dynamics in protein crystals gives rise to diffuse X-ray scattering – intensity beneath and between the Bragg peaks in diffraction experiments. Recent improvements in X-ray beamlines and detectors have created new opportunities for using diffuse scattering to understand protein dynamics. In this talk I will introduce some basic concepts about diffuse scattering from protein crystals and the connection to dynamics. I also will review some modern approaches to diffuse data collection, processing, analysis, modeling, and simulation.