Engineering Life: A Flipped Classroom with iBiology

Spring 2015 Syllabus

Course Days/Hours: 3pm-5pm on May 15, 18, 20, 22, 26, 27, 29

Location: Genentech Hall S261

Instructors: Ron Vale and James Fraser;

Course Description:

How did life evolve? How can understand the principles of biological systems to create new proteins, new chemicals, biological structures, cells and tissues? We will cover these topics in a “flipped course” where you will hear online lectures from scientific leaders in the field, read a paper, and then discuss as a group. We have chosen diverse topics within this subject area, since they provide a window into how scientists tackle problems using different approaches. We will meet for 7 sessions. Prior to each session, students and faculty will view the three parts of an iBiology talk (usually 3 x ~30 min segments) and read one research paper from the speaker which is also discussed in the talk. For the first session, two talks are assigned (they can be viewed at anytime prior to the course, as is true also of the other lectures). A series of prompt questions will be prepared to help guide student-faculty discussion as a group. One student and faculty member will be assigned as a discussion leader, but all students will be expected to be well prepared to engage in the discussion.

##Course structure##

2 students will serve as Discussion Leaders (pre-assigned below) for each class. Everyone should be prepared for class by having viewed the talks and read the paper carefully.

Discussion Leaders will need do advance work. The goal is to derive a set of questions that can lead to a provocative discussion with your classmates. Beyond our class, we would like the Discussion Leaders also to invest effort and produce a set of “Teaching Tools” which could be posted on the iBiology web site (with your name listed as having prepared them). Then, other teachers (mostly undergrad teachers) can benefit and lead discussions or make assignments for their classes on these lectures. It is also good opportunity for you to learn how to produce useful education material, which might prove useful later in your life. We can help you with revising your Teaching Tools (which will be part of the learning process) before we post them and have created an online guide to preparing Teaching Tools. Remember, the teaching tools overall are aimed for upper level undergraduate classes.

##Course goals/timelines:

For our UCSF class, our discussion time will focus primarily on the Research Lectures (part II and III of the iBiology Talk (or the main talk for Tejal Desai) and on the assigned paper. However, we also discuss the Introduction Talk from the point of view of the effectiveness of the presentation. Did you like the talk and the style of the speaker? What techniques did the speaker use well to engage the viewer or get a point across? To be successful in science, you will have to become a good communicator, so it is valuable to analyze what you think constitutes a successful talk (and also appreciate that there are various strategies for crafting a good talk).

If you want to talk to us about preparing your discussion session, please feel free to talk to us in advance with the faculty assigned for your discussion day.

#May 15#

##Jack Szostack - The Origins of Life on Earth##

Assigned Paper:

##Dianne Newman - Microbial Diversity and Evolution##

Assigned Paper:

#May 18#

##David Baker - Protein Design##

Assigned Paper:

#May 20#

##Chaitan Khosla - Polyketide Assembly Lines##

Assigned Paper:

#May 22#

##William Shih - Nanofabrication via Structural DNA##

Assigned Papers:

#May 26#

##Kristala Prather-Jones Synthetic Biology and Metabolic Engineering##

Assigned Paper:

#May 27#

##Sangeeta Bhatia Tissue Engineering##

Assigned Paper:

#May 29#

##Robert Langer Biomaterials and Delivery Systems##

Assigned paper:

##Desai/Bhisitkul Advancing the Treatment of Retinal Disease##

No paper assigned